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Letrozole

Letrozole

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Product Name:Letrozole
CAS No:112809-51-5
Molecular Formula:C17H11N5
Molecular Weight:285.31
Assay:98% min
Quality Standard:USP/ISO9001
Appearance:White or Off-white powder
Supply Ability:500-800kg/month
Storage:Store at 8℃-20℃, protect from moisture and light.

Chemical Properties of Letrozole:

Test Of Analysis Standard Of Analysis Results Of Analysis
Identification IR,HPLC,UV Conforms
Related substance A          ≤0.3% 0.02%
Other impurity          ≤0.1% 0.03%
All other impurity          ≤0.3% 0.11%
Organic volatile impurities Conforms with ICH requirements
Acetone Nmt 5000ppm    Conforms
Methanol Nmt 3000ppm Conforms
Ethanol Nmt 5000ppm Conforms
Residue On Ignition ≤0.1% 0.04%
Water by KF ≤0.3% 0.1%
Heavy metal ≤0.001% Conforms
Assay 98.0~102.0% 99.89%

Description:

Letrozole lowers estrogen levels in postmenopausal women,so it is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.Letrozle’s dosage 2.5mg per day.

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